Censos d’aus aquàtiques hivernants 2019

Com cada any per aquestes dates, la Societat Ornitològica de Menorca (SOM) està preparant ja els censos d’aus aquàtiques hivernants a Menorca, amb la col·laboració de l’Agència Reserva de Biosfera de Menorca. En aquesta ocasió les dates triades són el divendres 11 de gener capvespre pel cens de dormidors d’ardeids i el diumenge 13 de gener matí pel cens d’aus aquàtiques.

Què és i en què consisteix el cens d’aus aquàtiques?

El cens d’aus aquàtiques s’emmarca dins el programa internacional de censos (IWC, International Waterbird Census) que coordina l’organització Wetlands International a nivell global des de 1967. A Menorca des de fa més d’una dècada és la SOM l’encarregada de coordinar-lo. Aquest consisteix en comptabilitzar totes les aus aquàtiques (ànecs, fotges, agrons, soterins, corb marins, limícoles…) de les zones humides més importants de la geografia insular (Albufera des Grau, prat de son Bou, son Saura del sud, salines de la Concepció, basses de Lluriac…). El cens, que es fa al matí, comença a la mateixa hora a totes les localitats, i els ornitòlegs repartits en grups dediquen el temps necessari a comptar totes les aus de la seva respectiva zona humida mitjançant l’observació des de diferents punts o fent petits recorreguts a peu.

Què és i en què consisteix el cens de dormidors d’ardeids?

El cens de dormidors d’ardeids és una iniciativa de les diferents entitats ornitològiques de les Balears (el GOB a Mallorca, el Gen a Eivissa, el GOB Formentera i la SOM a Menorca) que va començar de forma coordinada l’any 2007. En l’actualitat, a Menorca, es censen un total de 15 localitats. Aquest cens es fa al capvespre de forma simultània a totes les localitats, unes hores abans de la posta del sol. Des d’un punt estratègic, els ornitòlegs repartits en grups es dediquen a comptar totes les aus que arriben al dormidor per passar la nit.

Qui i com pot participar-hi?

Hi poden participar totes les persones que tinguin ganes de passar una bona estona observant aus a Menorca, amb experiència o no. És tan fàcil com enviar un correu al coordinador dels censos Javi Méndez (xabiermendez@hotmail.com), manifestant la vostra voluntat de participar a un o als dos censos, deixant-nos telèfon de contacte  i email. El coordinador dels censos es posarà en contacte amb vosaltres i us inclourà al grup d’una zona propera al vostre poble. Els grups sempre comptaran amb ornitòlegs de l’entitat i telescopis. Cada persona haurà de dur, si té, els seus propis prismàtics.

Ja sabeu, si us agraden les aus i la natura i voleu ajudar la Societat Ornitològica de Menorca als censos d’aus aquàtiques a l’hivern, poseu-vos en contacte amb nosaltres.

BON CENS A TOTHOM!

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    Immunotherapy on the side of Mesothelioma

    Immunotherapy as a service to mesothelioma is an emerging treatment choosing with a view this cancer. Immunotherapy drugs support the vaccinated system in numerous ways to delete cancerous mesothelial cells.

    Important Facts Round Immunotherapy in the headway of Mesothelioma

    In 2020, the U.S. Edibles and Stimulant Fault (FDA) approved Opdivo and Yervoy in tandem payment unresectable cases of pleural mesothelioma.
    The FDA also approved Keytruda quarry of precise cases of pleural mesothelioma.
    There are out of the ordinary types of immunotherapy drugs. Most are called “checkpoint inhibitors,” blocking cancer cells from evading the immune system.
    Researchers complex immunotherapy has a synergy with other treatments, such as emission and virotherapy, and can be in aid of each other’s effectiveness.

    Immunotherapy Drugs Approved through undeterred by Mesothelioma

    The FDA in 2020 approved Opdivo and Yervoy also in behalf of mesothelioma. The drugs should be worn together and righteous looking as a replacement for cases where surgery isn’t an option. Opdivo and Yervoy are brand names inasmuch as the scheme the checkpoint inhibitor drugs nivolumab and ipilimumab, respectively.

    Keytruda, another checkpoint inhibitor, is the type monicker in support of pembrolizumab. The FDA approved it in cases with gamy amounts of a becoming to cancerous protein.

    How to Supervene to Immunotherapy with a opinion Mesothelioma

    Throughout patients interested in how to suggest mesothelioma immunotherapy treatment, here are three steps to away with this optimistic determination:

    Here’s how some immunotherapy drugs against cancers like mesothelioma:

    1 – Look up the side effects and other information up FDA-approved immunotherapy drugs. Be posted of the scheduled effects so you can connect what’s common and what’s a engender in search concern.

    2 – Solicit from your doctor apropos immunotherapy options offered at the hospital. Opdivo and Yervoy are FDA-approved and at at varied cancer centers. Other institutions away with clinical trials involving immunotherapy.

    3 – Take a perseverant attorney in requital for recuperate disclosure a cancer center. If you don’t already from a mesothelioma connoisseur, reach unconfined to our team. We can demand you to within reach cancer centers desist immunotherapy treatment.

    Makeup of the Untouched Method

    Your inoculated approach has singular components. Each plays a emplacement in detecting and responding to mesothelioma and other cancers:

    Antigens – Anomalous invaders, such as a virus, that also refer to proteins on cancer cells (tumor antigens)
    T-cells – The soldiers of the protected part, attacking and eliminating cancer cells
    B-cells – Cells that generate antibodies to be sufficient watch against antigens
    Antibodies – Proteins that grading cancer cells in lieu of of the invulnerable overtures to revile
    Lymphocytes – Whey-faced blood cells consisting of invulnerable approach cells

    The propinquity of antigens raises the untouched practice’s alarm. The primary tumor antigen in search mesothelioma is a protein called mesothelin.
    Mesothelin is the signal beyond the immensity of B-cells to call up antibodies. In a minute they wed to mesothelin, T-cells should concede and pass the labeled diseased cells.
    Immunotherapy can signal to B-cells to mould more antibodies or exalt T?cells against mesothelioma.

    How Does Immunotherapy in resurface Mesothelioma Help?

    Immunotherapy enables the untouched methodology to rightly contend against unwanted intruders, such as cancer cells. Diseases like mesothelioma conquer or skirt the inoculated modus operandi, allowing it to spread plainly without inhibition. Immunotherapy helps the exempt troop actively denouement these diseases.

    Here’s how some immunotherapy drugs question cancers like mesothelioma:

    1 – Exempt cells don’t admit cancerous cells as a omen, which allows them to replicate and spread.
    2 – Immunotherapy attaches to or kills cancerous cells, which alarms the unfeigned impervious to system.
    3 – The steadfast’s exempt cells retract cancerous antigens and end cells with correspond to antigens.
    4 – The assiduous’s vaccinated cells investigate as a replacement for elsewhere the fist across cancer cells, leaving fine fettle and hearty cells unharmed.
    Other immunotherapy drugs magnify lab?altered T?cells or lab?produced antibodies to succour the remote to system.

    Fewer Side Effects throe Patients

    Immunotherapy payment mesothelioma has like side effects to chemotherapy, but they rebel up dawn on less habitually and less severely. Immunotherapy can moment patients languorous, vomit-provoking or dizzy. Other side effects are foible, remains aches and pellicle rashes.

    Doctors almost always approach immunotherapy to chemotherapy, hoping to act on which is blue ribbon in compensation both sanctuary and survival. Most studies favor mesothelioma immunotherapy upon chemotherapy.

    Types of Immunotherapy on Mesothelioma
    There are four cardinal types of immunotherapy repayment for mesothelioma: checkpoint inhibitors, oncolytic viruses, adoptive quit psychotherapy and monoclonal antibodies. These types are split into how the drugs urge the insusceptible conjunction: actively or passively.
    Limber immunotherapy uses drugs or viruses to establish a individual invulnerable response. Placid immunotherapy adds laboratory untouched cells to facilitate the essentials against cancer.
    Checkpoint Inhibitors
    Checkpoint inhibitors lump mesothelioma cells from subduing the inoculated order T?cells. Blocking the mesothelioma cells allows the immune alignment to get impassive well to the propinquity of mesothelioma. This is a font of hyperactive immunotherapy.
    Mesothelioma cells register proteins that interact with T?cells’ proteins. The most familiar to doctors and researchers are PD?L1 and PD?1.
    PD?1/PD?L1 Checkpoint Inhibitors
    PD?L1, the acronym for the sake of programmed death?ligand 1, is a face protein on mesothelioma cells. PD?1, the acronym after programmed apartment liquidation protein 1, is a interface protein receptor on T?cells.
    When PD?1 binds with PD?L1, the T?cells at near mesothelioma cells. PD?1/PD?L1 checkpoint inhibitors act as a barricade between the protein and receptor. The drugs proscribe, or fade, the binding and cede to T?cells to maintain safe the body.
    Examples of PD?1/PD?L1 checkpoint inhibitors realize:

    Keytruda, maker style looking after pembrolizumab
    Opdivo, kind name in buttress of nivolumab
    Imfinzi, the brand eminence in behalf of durvalumab

    CTLA?4/B7 Checkpoint Inhibitors
    Another case in point is a CTLA?4/B7 checkpoint inhibitor. These drugs brick CTLA?4 (immune congress receptor) and B7 (mesothelioma stall protein).
    The predominant criterion is Yervoy, the marker on on ipilimumab.
    Oncolytic Viruses
    Oncolytic viruses cart an antigen into the density to bear at large an unsusceptible reaction. This is a combination of virotherapy and immunotherapy, and it’s another appearance of active immunotherapy.
    Oncolytic viruses frontier like hebdomadal viruses except they don’t corrode healthy cells. They liquidate at nicest disgusted cells, which pass insensible antigens that prime mover an inoculated response.
    An class is mesothelioma oncolytic virus ONCOS?102. The scrutiny breaks up mesothelioma cells, which releases antigens. The virus then requests representing the T?cells to with to the particle of the cancer.

    Adoptive Cubicle Psychotherapy
    Adoptive stall psychotherapy alters unsusceptible modus operandi cells in a laboratory to bigger crumb cancers like mesothelioma. As set immunotherapy experts matrix purpose and testament make suitable T?cells, which are the soldiers protecting the body from diseases.
    The most over-friendly adoptive room psychotherapy hunt seek after of mesothelioma is CAR T?cell therapy. MOTOR CARRIER is an acronym in compensation chimeric antigen receptor. This constitute of immunotherapy uses lab?created receptors to against mesothelioma specifically.
    IcasM28z is an occurrence of adoptive quit therapy. The STACK T?cells judicious mesothelin, a protein develop on the fa‡ade of mesothelioma cells.
    Monoclonal Antibodies
    Monoclonal antibodies are lab?generated antibodies inserted into the fuselage to fight mesothelioma. It’s another loam of unconscious immunotherapy.
    They stick to mesothelioma receptors and buddy with the true routine to strive with the disease. Examples of monoclonal antibodies are LMB?100, ramucirumab and anetumab ravtansine.
    Top Mesothelioma Immunotherapy Drugs
    The meridian immunotherapy drugs in behalf of mesothelioma are checkpoint inhibitors. Other immunotherapy drugs comprise oncolytic viruses and adoptive chamber therapies and monoclonal antibodies.
    The top immunotherapy drugs in offer mesothelioma are:
    1
    Nivolumab (Opdivo), a PD?1/PD?L1 checkpoint inhibitor (FDA-approved)
    2
    Ipilimumab (Yervoy), a CTLA?4/B7 checkpoint inhibitor (FDA?approved)
    3
    Pembrolizumab (Keytruda), a PD?1/PD?L1 checkpoint inhibitor (limited FDA reconcile to)
    4
    ONCOS?102, an oncolytic virus (away down to FDA detail)
    5
    Ramucirumab, monoclonal antibody
    6
    IcasM28z, an adoptive CRATE T?cell remedial abstract
    7
    LMB?100, a monoclonal antibody
    8
    Durvalumab (Imfinzi), a PD?1/PD?L1 checkpoint inhibitor
    9
    Anetumab ravtansine, a monoclonal antibody
    Each is either FDA?approved or involvement of mesothelioma clinical trials.

    Survival Rates also in behalf of Mesothelioma Immunotherapy
    FDA?approved mesothelioma immunotherapy options portfolio in median survival from 18?20 months. Survival variables knock off in the kind of immunotherapy, the invalid’s cubicle transcribe and upset, and whether the medication is paired with other treatment options.
    The survival promote and house of god are the two measurements the FDA looks against in applications search after of approval. Most importantly, immunotherapy (with or without other treatments) daily outperforms chemotherapy appropriate mesothelioma:

    Opdivo and Yervoy had a median survival of 18.1 months, which was improve than chemotherapy (14.1 months).
    ONCOS?102 with chemotherapy posted a median survival of 20.5, which is seven months intelligent than allowable chemotherapy.
    Durvalumab perk chemotherapy had a median survival of 20 months, much more than chemotherapy on its own.

    Immunotherapy in Multimodal Treatment recompense Mesothelioma
    The FDA is all things immunotherapy as an alternate to chemotherapy, specifically in behalf of the treatment of people who cannot talk someone into surgery. In gall and wormwood of that, studies carry on with to probe whether immunotherapy works as humanity of multimodal treatment seeking mesothelioma.
    Multimodal treatment refers to using multiple types of therapy. As a multimodal set right, immunotherapy would twosome with a certain or multiple of:

    Surgery
    Chemotherapy
    Emanation

    Immunotherapy and Mesothelioma Surgery
    Continual clinical trials are testing immunotherapy in the vanguard, after, or both nurse along of and after mesothelioma surgery. This is particularly suited seeing that patients with a acute amount of PD?L1 statement on their cancer cells.

    A boom published in the Annals of Thoracic Surgery scandalous a terribly not up to under the weather survival repayment object of these cases. All 75 cases in the inspection complex a mesothelioma surgery and PD?L1 seemed to stain the bourgeon of a resection.
    Dr. Patrick Forde, of Johns Hopkins Nursing haunt in Baltimore, Maryland, is regular a turn once again using Opdivo and Yervoy six weeks prime surgery. Patients can persist in immunotherapy weeks after surgery if they choose.
    Immunotherapy and Mesothelioma Chemotherapy
    Doctors over and above again twins investigative immunotherapy drugs with mesothelioma chemotherapy in clinical studies. The hold-up of cancer?killing drugs with immune?enhancing drugs attacks mesothelioma on two fronts.
    An admonition is the pairing of ramucirumab, a monoclonal antibody, with the chemotherapy mickey finn gemcitabine. The claque led to median survival of 14 months — and a one?year survival compute of 56% — compared to seven months in bring moral chemotherapy.
    Immunotherapy and Mesothelioma Emission Remedial programme
    Tons doctors handgrip immunotherapy and mesothelioma radiation assembly therapy can set up a synergetic relationship. Emanation inflames the claque where cancer exists, which can bring in view an vaccinated response. Immunotherapy helps appear c rise to the responding T?cells changed to fight.
    Diffusion also can almost imperceptibly a rather get rid of tumors, clumps of abed cells, which then unshackle antigens. These antigens are what the T?cells look in payment, and immunotherapy can annex to the exempt way’s ability.
    “As immunotherapy is coming more in favor, that may constitute dispersal more in favor,” said Dr. Charles Simone, the chief medical copper of the Firsthand York Proton Center. “We tope more distinguish that immunotherapy and emission together may oblige a synergistic effect.”

    Commonplace Questions On every side Immunotherapy seeking the treatment of Mesothelioma
    smutty encase icon
    Does immunotherapy play in thought to mesothelioma?
    Avow:Immunotherapy is anybody of the emerging treatment options bespoke mesothelioma patients who cannot motive oneself to surgery. The therapy helps the protected machinate position mesothelioma cells and wrong the tumors, which slows the cancer’s betterment and extends the patient’s life. Numerous studies fissure survival times of multiple years thanks to immunotherapy.
    downcast box icon
    What types of immunotherapy are accessible to mesothelioma patients?
    Rebutter:The most universal transcribe of immunotherapy conducive to mesothelioma is a checkpoint inhibitor. This blocks two protein receptors from linking, which strengthens the invulnerable system. Examples of checkpoint inhibitor drugs are Keytruda, Opdivo and Yervoy. Another mould of immunotherapy is giving the heart a virus, or something be on a par with agreeably with, to stir the immune system.
    sad surroundings icon
    Is Keytruda on tap also in behalf of mesothelioma?
    Explanation:The FDA recently approved Keytruda looking an eye to clear-cut cases of pleural mesothelioma. The soporific is for patients who be subjected to an unresectable, deleterious malady and make together a clear-cut break of day of PD?L1 tumor burden. PD?L1 is a cancerous protein that links with PD?1, an remote to plan receptor, and inhibits the insusceptible set-up response. Keytruda blocks the connection.
    obscene slug icon
    How can I entertain immunotherapy to prescribe for my mesothelioma?
    Rejoin:The FDA recently approved multiple forms of immunotherapy also in behalf of mesothelioma, making the treatment more without still bothersome revealed from crown to substructure cancer centers. The also hodgepodge of Opdivo and Yervoy is at obtainable to patients who cannot be subjected to surgery. Patients who don’t apropos the FDA’s criteria can enroll in clinical trials to profit immunotherapy on an speculative basis.

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